Scientist II

Job Description

Job Summary:

• The Scientist II will join the Analytical R&D Department at Client at our Life Sciences R&D facility in St. Louis.
• In this role, you will be part of an active, multidisciplinary group of scientists dedicated to providing high level analytical support to product development scientists in R&D, manufacturing groups, and special project teams.
• You will be expected to lead development of LC-MS assays for the quantitation of proteins in complex mixtures.
• Additionally, you will perform advanced characterization of large biomolecules including monoclonal antibodies, multispecifics, and antibody drug conjugates.

Required Qualifications:

• BS in Chemistry or related field.
• Demonstrated hands-on proficiency with advanced instrumentation, such as with high resolution and triple quadrupole LC-MS platforms.
• Expertise with a variety of enzymatic and chemical methods of sample preparation for large biomolecule LC-MS, such as digestion, enrichment, depletion, and labelling.
• The ability to work and communicate effectively both independently and in a team-oriented environment.

Preferred Qualifications:

• Demonstrated hands-on proficiency with HPLC instrumentation and chromatographic software such as Empower and Chromeleon.
• Strong experience with a variety of enzymatic and chemical methods of sample preparation for large biomolecule LC-MS, such as digestion, enrichment, depletion, and labelling.

Must have:

• 2-5 years of industry experience.
• Mass Spectrometry experience.
• 80% lab based: making reagents, doing sample prep, pipetting.
• Independent worker preferred.