Research Associate II

Job Description

Job Summary:

• To provide technical laboratory research effort in support of multiple projects focused on expedited evaluation and the clinical translation of therapies.

Duties and Responsibilities:

• siRNA drug candidate screening, hit identification, and lead optimization.
• Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; RNA extraction and RT-qPCR.
• Analyze data and present the results in group meetings.
• Maintain clear experimental records in laboratory notebooks; write SOPs and other technical reports as needed.
• Work closely with research team members to quickly and effectively address critical questions related to the efficacy of our drugs.
• Review literature and provide insights to research directions, while predominantly making hands-on contributions to the research.

Qualifications:

• Master’s in Cell and Molecular Biology or Pharmaceutical Sciences.
• 4+ years of relevant drug discovery laboratory experience in industrial or academic environment is preferred.
• Experience in cellular and molecular biology is essential (e.g., mammalian cell culture, cell-based assays, quantitative real-time PCR).
• Experience with primary human adipocytes and hepatocytes culture is preferred.
• Experience with advanced in vitro model systems including organoids and other 3D culture systems is highly preferred.
• Experience with RNAi and in vitro screening is preferred.
• Candidate must have strong oral and written communication skills, strong work ethics and demonstrated to be an effective contributor to group projects in a team-oriented environment.
• The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected.