Scientist I
Job Description
Job Summary:
- We are seeking a highly motivated individual with a strong background in mammalian cell culture to support research and innovation within our Cell Line Development expression platform.
- The research focus will center on improving components, methodologies, and platforms used in generating recombinant CHO cell lines expressing complex biologics.
Duties and Responsibilities:
- Candidates highly experienced in cellular and/or molecular biology are encouraged to apply.
- Prior experience in CHO cell biology is highly desired.
- Design, execute and analyze platform research studies to support process development activities which aim to reduce overall timelines while improving cell line productivity and product quality.
- Assist in generation of engineered mammalian cell lines (transfection pools, clones) expressing candidate biotherapeutics.
- Assist in several studies simultaneously to optimize cell line generation processes.
- Perform mammalian cell culture techniques: sterile technique, cell counting, passaging, cryopreservation, etc.
- Perform basic molecular biology techniques: DNA plasmid preparation, PCR, restriction enzyme digestion, etc.
- Self-motivated with excellent attention to detail and superb organizational skills, having a proven ability to work in a highly collaborative environment and communicate transversally.
- Flexibility, adjusting to a fast-paced, goal-oriented environment and willingness to expand and broaden one’s skillset.
- Prepare reports, presentations, and data sets to effectively communicate results, progress and plans.
Basic Qualifications:
- PhD with 0-2 years of relevant experience in Biology, Cellular Biology, Molecular Biology or Master’s Degree /Bachelor’s Degree with equivalent industry experience.
Preferred Qualifications:
- Experience in suspension culture of CHO cell lines in a pharmaceutical or biotechnology setting.
- Experience and knowledge of molecular techniques including gene editing, copy number analysis, Gibson assembly etc.