Biologist

Job Description

Job Summary:

• The in vivo pharmacology Scientist/Senior Scientist/Principal Scientist will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of Client therapeutic candidates for genetic medicines.

Duties & Responsibilities:

• Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
• Assist in the development and characterization of Client in vivo models.
• Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to development.
• Provide written and verbal communication of work in study reports and team meetings.
• Keep and maintain accurate and timely documentation of all practical work: completion of electronic notebook in alignment with Client procedure quality standards and Good Documentation Practices.
• Ensure compliance with all health and safety regulations.

Required Qualifications:

• Scientist/Senior Scientist/Principal Scientist – In Vivo Pharmacology.
• B.S/MS in life sciences (e.g., biology, neuroscience, or related field).
• Or 3-5 years experience working in pharmaceutical industry or contract research organization.

Required Skills:

• Hands on experience of rodent handling, dosing, and blood collection of mice and rats including but not limited to: subcutaneous (SC), intravenous (IV), & intraperitoneal (IP) injections, and submandibular, venipuncture, & cardiac puncture bleeds.
• Experience with gross necropsies, tissue dissection, and trimming and processing.
• Ability to adapt and exercise flexibility for changing platform needs, workflows, and projects including the availability to provide the occassional night, weekend, or holiday hours.
• Ability to craft, complete and interpret experiments independently, and to advance scientific understanding.
• Excellent communication skills and effective in collaborating across functional boundaries and in team environment.
• Strong organization skills, attention to detail, critical thinking, multitasking, desire to learn new techniques and contribute to innovative projects in a fast-paced working environment.
• Experience in processing, organizing, analyzing and visualizing data and information from disparate sources and ability to extract insight from data.