Associate Scientist – Biology II

Job Description

Job Summary:

• We are seeking a highly motivated Associate Scientist (Contract) to support our Protein Sciences team.
• This individual will contribute as a hands-on laboratory scientist, executing protein production, purification, and analytical workflows that support multiple CAR-T and cell therapy programs.
  This is a 100% bench-focused, individual contributor role.
• The successful candidate will work closely with scientists across Protein Science and Research to generate high-quality data and reagents, while contributing to efficient laboratory operations and experimental execution.

Duties and Responsibilities:

Protein Production & Purification:

• Execute recombinant protein expression and purification workflows across multiple expression systems (e.g., mammalian cell culture, transient transfections).
• Perform protein purification using AKTA chromatography systems (affinity, SEC, ion exchange.
• Maintain cell cultures and support transfection workflows.

Analytical Characterization:

• Document and summarize experimental data clearly to support team decision-making.
• Perform biochemical and biophysical characterization of proteins and antibodies, including:
• SDS-PAGE and Western blot.
• UPLC/HPLC-based purity assessment.
• Binding assays (e.g., Octet/BLI).

Protein Modification & Assay Support:

• Perform antibody and protein conjugation workflows with appropriate analytical follow-up.
• Prepare reagents and materials to support downstream functional assays (e.g., flow cytometry or cell-based assays in collaboration with Cell Biology partners).

Lab Operations & Execution:

• Maintain organized lab practices, including reagents, consumables, and shared equipment.
• Ensure accurate experimental documentation in electronic lab notebooks and LIMS.
• Follow established SOPs and contribute to maintaining reproducibility and data quality standards.

Collaboration:

• Work closely with cross-functional partners to execute experiments aligned with defined protocols and timelines.
• Communicate experimental progress and results effectively to project teams.

Basic Qualifications:

• Bachelor’s or Master’s degree in Biochemistry, Molecular Biology, Protein Science, or related field.
• 2–4+ years of relevant hands-on laboratory experience in academic or industry settings.

Preferred Qualifications:

• Experience with recombinant protein expression and purification workflows.
• Hands-on experience with AKTA systems and chromatography methods.
• Familiarity with protein characterization techniques (SDS-PAGE, HPLC, BLI/Octet, etc.).
• Experience with mammalian cell culture and transfections.
• Strong attention to detail and commitment to high-quality data generation and documentation.
• Ability to follow protocols, troubleshoot at the experiment level, and work effectively in a fast-paced lab environment.

Key Characteristics for Success in This Role:

• Strong hands-on bench execution skills.
• High level of organization and reproducibility.
• Ability to independently execute experiments with appropriate controls.
• Collaborative mindset and willingness to support team priorities.