Research Scientist I

Job Description

Duties and Responsibilities:

• Conduct siRNA drug candidate screening, hit identification, and lead optimization.
• Apply cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening (e.g., transfection); cell-based assays; PCR.
• Support in vivo drug candidate testing (e.g., mouse dosing; sample analysis).
• Innovate and advance research projects to further optimize the siRNA platform.
• Generate high-quality technical documentation and communicate findings internally and externally.

Qualifications:

• MS w/2 years experience or PhD w/1 year experience in cell or molecular biology (or a related field) – experience must be post-degree experience preferably in drug discovery and in an industry setting.
• Expertise in cellular and molecular biology is essential (e.g., mammalian cell culture; cell-based assays; qPCR).
• Experience with RNA-seq, library preparation and immunoprecipitation-based workflow are desired.
• Proficiency in animal handling, dosing, and necropsy is desired.
• Demonstrated ability to execute and interpret experiments rigorously, deliver reliable results and drive projects aggressively towards defined goals.
• A strong team player with a high energy and a passion for contributing to the discovery and development of Client therapeutics.
• Strong oral and written communication skills with a proven ability to contribute effectively to group projects in a team-oriented environment.
• Innovative and creative; takes initiative.