Engineer – Formulation Sciences

Job Description

Job Summary:

• We are seeking an Engineer to join our Formulation Sciences team focused on lipid nanoparticle (LNP) discovery and development for Verve’s Client CRISPR-based gene editing therapies.
• The successful candidate will be responsible for supporting LNP process development, scale-up, and characterization working as part of a multidisciplinary fast-paced team environment.
• The ideal candidate will have some process development industry experience with a desire to contribute to a team focused on championing nano medicinal products and developing manufacturing solutions based on strong scientific principles.

Duties & Responsibilities:

• Support the design, manufacturing and characterization of lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs).
• Support the design and execution of a wide range of experiments including DoEs to advance LNP technology and process development.
• Participate in defining equipment specification/selection, draft procedures and recommended operating parameters/ranges.
• Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports.
• Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory.
• Multi-task across several projects and manage time effectively to achieve results.
• Collaborate with multiple cross-functional teams and execute other duties as assigned.

Required Qualifications:

• Engineer, Formulation Sciences.

Required Skills & Qualifications:

• Bachelor’s/Master’s degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field with 2+ years of relevant industry experience.
• Experience with lipid nanoparticle formulations and analytical characterization methods (Preferred).
• Strong problem-solving skills, and creative/innovative approach in problem solving.
• Ability to work independently and in very dynamic interdisciplinary team environments.
• Proven record in working with partners/collaborators is desirable.
• Organized, detail-oriented, and innovative self-starter who continuously seeks to improve existing laboratory methods and processes.
• Effective verbal and written communication skills; proficiency in literature search and relevant computer software skills are required.
• Knowledge of practices and equipment used to run manufacturing processes in a GMP environment, including TFF, sterile filtration, single-use technology, and sterile/aseptic processing preferred.