Chemist

Job Description

Job Summary:

• Provide hands-on technical support to Column Production, primarily focused on troubleshooting column packing and testing failures, analyzing chromatographic performance, and supporting process improvements.
• The position requires strong analytical and chromatography experience with a working understanding of polymer chemistry, chromatography resins, silica stationary phases, and surface chemistry to evaluate how material properties may affect column performance.

Duties & Responsibilities:

• Provide day-to-day technical troubleshooting support for column packing, testing, and qualification failures.
• Investigate issues involving efficiency, peak asymmetry, resolution, retention, selectivity, backpressure, and flow behavior.
• Analyze chromatograms, pressure profiles, packing parameters, manufacturing records, and qualification data to identify potential root causes.
• Differentiate between failures related to packing, equipment, column hardware, testing conditions, stationary-phase properties, or manufacturing execution.
• Support optimization of packing pressure, flow rate, slurry conditions, equipment parameters, and other critical manufacturing variables.
• Design and execute experiments to improve column packing reproducibility, first-pass yield, and process robustness.
• Apply working knowledge of polymer/resin and silica chemistry to understand potential material-related impacts on column performance.
• Work directly with Manufacturing Technicians, SMEs, RQ, Engineering, Quality, and R&D during troubleshooting activities.
• Document investigations, experimental results, and technical recommendations.
• Support development and revision of SOPs, work instructions, troubleshooting guides, and manufacturing documentation.
• Assist with training Manufacturing personnel on improved troubleshooting methods and process changes.

Required Skills:

• Bachelor’s or Master’s degree in Analytical Chemistry or Polymer Chemistry.
• 3 years of relevant industry experience in chromatography, process development, analytical development, or manufacturing support.
• Hands-on experience with HPLC, IC, or related chromatography systems strongly preferred.
• Experience troubleshooting chromatography columns, packing processes, or analytical systems is highly desirable.
• Working knowledge of polymer chemistry, chromatography resins, silica materials, and surface chemistry.
• Strong analytical, data interpretation, root cause investigation, and problem-solving skills.
• Experience with DOE, JMP, or statistical data analysis is a plus.
• Experience working in GMP, ISO, or other regulated manufacturing environments preferred.
• Must be comfortable working hands-on with Manufacturing personnel and equipment in a production environment.