Job Description
Job Summary:
- Scientist III (Contract) to support high-impact research and development programs within the Sample Preparation R&D team.
- This 1-year contract role will focus on developing and optimizing bead-based nucleic acid extraction and direct-to-qPCR workflows for advanced molecular biology applications.
- The ideal candidate will bring strong hands-on experience with magnetic bead–based nucleic acid purification and qPCR and will contribute to multiple R&D initiatives aimed at improving sensitivity, speed, and workflow efficiency for nucleic acid extraction and detection across research and applied markets.
Duties & Responsibilities:
- Design, execute, and analyze laboratory experiments supporting bead-based DNA and RNA extraction workflows.
- Develop and optimize lysis-to-qPCR and direct-to-PCR sample preparation workflows, including Cells-to-CT–style approaches.
- Perform qPCR and RT-qPCR assays to evaluate workflow performance, sensitivity, and robustness.
- Support development of sample preparation solutions for complex biological matrices (e.g., plasma, serum, cell culture media, bodily fluids).
- Document experimental results clearly and contribute to technical reports and data summaries.
- Collaborate with cross-functional partners including assay development, automation, and product development teams.
- Adhere to laboratory safety, quality, and data integrity standards.
Required Qualifications:
- 1+ year Hands-on experience with magnetic bead–based nucleic acid extraction (DNA and/or RNA).
- 3+ months Experience with direct-to-PCR or lysis-only workflows.
- 1+ year Strong working knowledge of qPCR and RT-qPCR, including assay setup, data analysis, and troubleshooting.
- 6+ months Experience working with biological samples and chemical lysis methods.
- Ability to independently plan and execute experiments while meeting project timelines.
- Ability to use basic analytical techniques and equipment to formulate buffers (molarity calculations, pH meter, balances, etc.)
- Experience with Excel and PowerPoint.
- Education experience does count toward the required experience in the above skills.
Preferred Qualifications:
- Experience with automated sample preparation platforms (e.g., Kingfishers systems).
- Experience working in an R&D or product development laboratory environment.
- Experience JMP statistical analysis software.
Knowledge, Skills, Abilities:
- Strong independent experimental design and problem-solving skills.
- Excellent written and verbal communication abilities.
- High attention to detail and data quality.
- Ability to work effectively in a fast-paced, collaborative environment.
Physical Requirements:
- Able to pipet, work in a BSL2 laboratory, lift up to 20 lbs.
Required Education:
- Bachelor’s degree with 4+ years, or Master’s degree with 2+ years, of relevant experience in molecular biology, biotechnology, biochemistry, or a related field.