Bench Scientist – II

Job Description

Job Summary:

• Biomedicine Design is seeking a laboratory scientist (contingent worker) to support therapeutic antibody discovery programs.
• This role focuses on executing essential molecular biology workflows that support B cell-based discovery campaigns, immune library generation, and sequence characterization.
• Working in a collaborative laboratory environment, the successful candidate will execute established molecular biology protocols—such as nucleic acid isolation, PCR amplification, cloning, and sample purification—and assist in preparing samples for Next-Generation Sequencing (NGS) and automated workflows.
• This is an exciting opportunity for an early-career scientist to apply core molecular biology skills to biotherapeutic discovery while Producting hands-on exposure to cutting-edge sequencing and laboratory automation technologies.

Duties and Responsibilities:

Molecular biology support:

• Execute established molecular biology workflows, including RNA/DNA isolation from cell samples, reverse transcription (RT), PCR amplification, and standard molecular cloning.

Library preparation & sample processing:

• Assist with the generation and cleanup of immune libraries and amplicons using magnetic beads (e.g., SPRI), restriction digests, and gel purification.

Sequencing & automation assistance:

• Support sample preparation and quality control (quantification, sizing) for Next-Generation Sequencing (NGS); assist with running routine protocols on automated liquid handlers.

Laboratory documentation & operations:

• Maintain clear, accurate records of experimental procedures and results in electronic laboratory notebooks (ELN); support reagent inventory and daily bench readiness.

Team collaboration:

• Prioritize tasks across active discovery timelines and communicate experimental progress and observations to project teammates.

Education Level:

• Bachelor’s (B.S.) or Master’s (M.S.) degree in Molecular Biology, Biochemistry, Biotechnology, Biology, or a related life sciences discipline.

Years of Experience:

• 0 – 2+ years of hands-on laboratory experience in an academic, biotechnology, or pharmaceutical research setting.

Required Skills:

• Hands-on experience with standard molecular biology techniques (such as DNA/RNA extraction, PCR setup, and agarose gel electrophoresis).
• Familiarity with routine nucleic acid purification (e.g., column- or magnetic bead-based cleanups) and quantification methods (e.g., NanoDrop, Qubit).
• Working knowledge of standard molecular cloning principles (e.g., primer design, restriction digests, or Gibson assembly).
• Strong attention to detail, good organizational skills, and thorough record-keeping habits.

Nice-to-Have Skills (Preferred):

• Familiarity with or interest in laboratory automation and automated liquid handling platforms (e.g., Hamilton, Biomek, Opentrons).
• Familiarity with Next-Generation Sequencing (NGS) library preparation workflows and QC (e.g., TapeStation/Bioanalyzer).
• Experience with or interest in utilizing Python and/or AI tools for data analysis or automation scripting.
• Exposure to B cell workflows, immunology concepts, or antibody discovery methods.