Research Associate – Scientific

Cambridge, Massachusetts
July 29, 2026
$32 / hour
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Job Description

Job Summary:

  • The Research Associate scientist will be a key member of the Translational Development Team in Cambridge, MA, utilizing high-dimensional spatial and genomic profiling tools to address translational knowledge gaps across our development pipelines.
  • The ideal candidate brings hands-on experience in one or more of these areas, strong foundational lab skills, and the ability to work independently and collaboratively to meet project goals.

Duties and Responsibilities:

  • Operate, maintain, and troubleshoot spatial profiling instruments (Phenocycler Fusion, Visium, and related platforms).
  • Prepare samples and reagents, including validation and slide preparation.
  • Support genomic and histological assay workflows.
  • Maintain accurate records, manage reagent/sample inventory, and perform routine data transfers.
  • Assist in the development and optimization of new spatial technology reagents and protocols.

Required Education & Experience:

  • Bachelor’s degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields.
  • 3+ years of hands-on laboratory experience.
  • Quick learner with genuine openness to new technologies and methodologies.
  • Excellent hands-on technical and organizational skills, with strong attention to detail and quality.
  • Effective and timely communication skills with both peers and senior leadership.
  • Demonstrated ability to meet project goals and timelines.
  • Experience in a collaborative team environment.

Must Have – Spatial & Advanced Profiling (Requirement):

  • Hands-on experience with spatial transcriptomics or proteomics platforms, including one or more of: Phenocycler /CODEX (Akoya), COMET (Lunaphore), Visium (10x Genomics), CosMx (NanoString/Bruker), Xenium (10x Genomics), or comparable technologies.
  • Familiarity with spatial assay workflows: antibody panel design, staining optimization, and image acquisition/analysis.
  • Experience with single-cell RNA sequencing (scRNA-seq) or bulk RNA/DNA sequencing using Illumina platforms.
  • Familiarity with library preparation, sequencing workflows, DV200 test.

Preferred – Histology/Pathology, Cell Culture (Secondary Preference):

  • Experience with multiplex immunofluorescence (mIF), IHC, or ISH workflows, particularly on automated autostainer platforms (e.g., Leica Bond, Ventana).
  • Basic proficiency in mammalian culture and standard laboratory assays including single cell cloning, CRISPR-Cas9, protein immunoblot and flow cytometry (4+ channels).

Working Conditions:

  • The position is primarily in a laboratory environment and may involve working with hazardous materials, including human tissue and blood samples.
  • Adherence to all relevant safety protocols and Client laboratory standards is required.

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