Bench Scientist II

Job Description

Job Summary:

• Biomedicine Design’s Endogenous Antibody Discovery Group is seeking a Senior Associate Scientist (contingent worker) to support antibody discovery projects focused on B cell-based workflows.
• This role will contribute to therapeutic antibody discovery campaigns using rodent immunization, serum titer screening, B cell sorting by flow cytometry, immune library generation, and hybridoma-based methods.
• The successful candidate will execute established laboratory workflows that support immunization-based discovery, including rodent selection, immunization strategies (protein, cell-based, and genetic), serum response evaluation by ELISA, flow cytometry, VH/VL molecular cloning, immune library generation and quality control, electrofusion, and hybridoma culture and screening.
• The role will also contribute to the evaluation and implementation of new technologies that enhance immunization and flow cytometry-based antibody discovery workflows in collaboration with other group members.

Duties and Responsibilities:

• Provide laboratory support for therapeutic antibody discovery campaigns using flow cytometry, immune library generation, and hybridoma-based methods.
• Execute established workflows to support rodent immunization studies, serum titer screening, B cell sorting, molecular cloning, and related sample processing activities.
• Maintain reagent inventories, prepare laboratory materials, and ensure operational readiness for discovery activities.
• Document experimental procedures, results, and observations accurately in laboratory records and internal data systems.
• Summarize data and communicate key findings, experimental progress, and campaign outcomes to project teams.

Education and Experience:

• Bachelor’s degree in biology, immunology, molecular biology, biochemistry, or a related scientific discipline, with at least 2 years of full-time laboratory experience in an academic or industry setting.
• Experience with flow cytometry-based analysis or cell sorting.
• Experience with laboratory automation or high-throughput workflows.
• Experience working with rodents, particularly mice, in a research setting.
• Experience working with hybridoma generation, culture, or screening workflows.
• Hands-on experience supporting antibody discovery workflows, including flow cytometry, B cell-based methods, or hybridoma-based screening.
• Experience with laboratory documentation, data organization, and communicating experimental results clearly to project teams.

Knowledge, Skills and Abilities:

• Working knowledge of molecular biology techniques such as PCR, cloning, and immune library generation or related sample preparation workflows.
• Strong laboratory organization skills, including reagent handling, inventory support, and maintaining materials needed for experimental workflows.

Interview Process:

• Initial phone/video interview with Hiring Manager.
• Onsite panel interview with team members.