Scientist III

Job Description

Job Summary:

• This role will leverage and develop the next phase of automation development in mass spectrometry supporting the Cell Engineering and Analytical Sciences group.
• The role blends hands-on robotic operations, sample preparation, method development, and data analysis.

Duties and Responsibilities:

• Operating and validating robotic runs; monitoring performance, documenting deviations, and driving corrective action.
• Develop and implement mass spectrometry assays to optimize protein expression levels, protein quality, and quantitation of biotherapeutics.
• Ensure accuracy and success of MS experiments through expertise in sample preparation.
• Deploying, optimizing, maintaining, and continuously improving high-throughput workflows using liquid-handling robots and integrated automation work cells.
• Analyze antibodies using pep Product mapping, intact mass analysis, native mass spectrometry, and acoustic ejection mass spectrometry.
• Troubleshooting instrumentation by coordinating with internal subject matter experts and external vendors to perform root cause analysis based on detailed scientific and technical investigations.
• Prepare and present scientific findings and recommendations to internal customers, project teams, and senior management.

Qualifications:

• Creative, independent problem‐solver with strong attention to detail and the ability to plan, prioritize, and deliver in a fast‐paced environment.
• A minimum of a B.S. in Biology, Chemistry, Computer Science, Engineering, or a related field is requited.
• An advanced degree is preferred.
• Strong organizational, time management, and interpersonal skills (both written and oral), and a commitment in close collaboration with scientists, vendors, and end users across seniority levels.
• Previous hands on experience with executing protocols, pipetting and protein sample handling skills.
• Experience with operating liquid handling systems (e.g., Hamilton, Tecan, Beckman) and/or basic programming experience (Python, JavaScript, R, C++/C#).
• Hands on experience with LC-MS and associated sample preparation.