Research and Development Scientist IV

Job Description

Duties and Responsibilities:

• Support membrane protein expression and purification.
• Conduct protein production, purification and characterization.
• Characterization and quality check of membrane proteins to support biotherapeutics development.
• Collaborate effectively in a multi-team environment.
• Contribute to both internal and external efforts in membrane protein production.

Education and Experience:

• Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required.

Required Experience and Skills:

• Experience with membrane protein expression and optimization, purification, and characterization of proteins.
• Well-versed with analytical characterization to determine quality, conformation, purity and stability.
• Knowledge of protein expression construct design and optimization, and expression platforms.
• Excellent communication skills to collaborate with internal and external partners.

Preferred Experience and Skills:

• Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs.
• Experience in independently operating AKTA FPLC and analytical HPLC instruments.
• Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery.
• Knowledge and experience with CROs for protein production.