Job Description
Job Summary:
- To provide technical laboratory research effort in support of multiple projects focused on expedited evaluation and the clinical translation of therapies.
Responsibilities:
- siRNA drug candidate screening, hit identification, and lead optimization.
- Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; RNA extraction and RT-qPCR.
- In vivo drug candidate testing (e.g., mouse dosing; sample analysis).
- Analyse data and present the results in group meetings.
- Maintain clear experimental records in laboratory notebooks; write SOPs and other technical reports as needed.
- Work closely with research team members to quickly and effectively address critical questions related to the efficacy of our drugs.
- Review literature and provide insights to research directions, while predominantly making hands-on contributions to the research.
Qualifications:
- Master’s Degree in Cell and Molecular Biology or Pharmaceutical Sciences.
- 4 years of relevant drug discovery laboratory experience in industrial or academic environment is preferred.
- Experience in cellular and molecular biology is essential (e.g., mammalian cell culture, cell-based assays, quantitative real-time PCR).
- Experience with in vivo methodologies is a plus (e.g., mouse handling, subcutaneous injection, intravenous injection, necropsy, sample analysis, histology).
- Experience with RNAi and in vitro screening is preferred.
- Candidate must have strong oral and written communication skills, strong work ethics and demonstrated to be an effective contributor to group projects in a team-oriented environment.
- The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected.