Job Description
Job Summary:
- Client is a leading company in Global Healthcare that discovers, develops, produces, and markets innovative therapies to help protect health and enhance people’s lives.
- We are seeking a highly motivated in-vivo pharmacologist to join the Type 2 Immunology Cluster within the Immunology and Inflammation Therapeutic Area located in Cambridge, MA.
- The ideal candidate will possess a strong background in in-vivo pharmacology, contributing technical skills and functional knowledge.
- The candidate will also be involved in the design, overall conduct, and the reporting of in-vivo pharmacology study results to project teams.
- The position is a hands-on, laboratory-based role that requires strong communication skills, attention to detail, a results-driven way of working, and ability to work both individually and in a team environment, and to work across functions.
- A successful candidate is expected to analyze, record and report data, be able to develop and learn new techniques, and be able to multi-task between multiple projects.
Duties and Responsibilities:
- Responsible for designing and performing in-vivo pharmacology experiments in support of project team goals.
- This includes study design, data collection and recording, communication of results, and report writing.
- Summarize and present study data to project teams within established timelines.
- Generate specific pharmacology reports based on studies performed to support IND submission.
- Capacity to use established procedures and methodologies with the ability to transform novel approaches into routine practice.
- Must be a technical contributor.
- Ability to troubleshoot experiments.
- Support the development of disease relevant in-vivo models.
- Must be well organized and detail oriented.
- Must have meticulous record keeping skills according to client quality guidelines.
- Maintain a thorough and compliant laboratory notebook.
- Must adhere to all federal, local, and Client animal welfare guidelines.
- Must be capable of working alone and in a team environment.
Education and Experience:
- Master’s Degree plus a minimum of 0 to 3 years of relevant research experience in a biopharmaceutical setting OR a Bachelor’s Degree plus a minimum of 2 to 5 years of relevant research experience in a biopharmaceutical setting.
- PhD candidate will be accepted, min 2+ years of experience.
- ELN and scientific record-keeping.
- Animal handling and dosing techniques.
- Experience with in-vivo immunology models.
- Previous experience with models of respiratory disease, dermatitis models, and smoke induced COPD models is a plus.
- Experience in various dosing methods, blood collection techniques, and tissue harvest are required.
- Experience with compound or reagent preparation.
Knowledge, Skills and Abilities:
- Ability to apply technical skills to complete assigned work as a competent technical contributor.
- Ability to design and perform in-vivo pharmacology experiments.
- Ability to work under moderate supervision with regular review of results and methods utilized.
- Ability to present study related results to project teams.
- Proven ability to work in a dynamic, customer-focused and results-oriented environment.
Key Focus Areas:
COPD and Respiratory Disease Models:
- Primary responsibility will be COPD studies in mice (~50% of workload), along with other respiratory disease models.
Pharmacology Focus:
- Role involves working with pharmacological compounds in preclinical studies.
Animal Work:
- Direct work with mice, including – Dosing (various methods), blood collection, tissue harvest.
- Compound/reagent preparation.