Research Associate Scientist II

Job Description

Job Summary:

• We are seeking a motivated Associate Scientist to join the Process Sciences group, supporting the development and execution of oligonucleotide Product manufacturing processes for siRNA therapeutics.
• This entry-level role is ideal for a recent graduate or early-career scientist looking to Product hands-on experience in processing, manufacturing, and process development of oligonucleotide Product therapeutics within a collaborative, fast-paced environment.
• The Associate Scientist I will work closely with senior scientists and engineers to execute laboratory operations, collect and document data, and support process optimization and technology transfer activities.
• This position is onsite and primarily located in Cambridge, MA.

Duties and Responsibilities:

• Support processing activities for oligonucleotide Product manufacturing under guidance from senior staff.
• Execute laboratory-scale and pilot-scale processes to support research and in-house material needs.
• Perform routine in-process analytical tests (e.g., pH, conductivity, UV, basic chromatography).
• Assist in the preparation, execution, and documentation of non-GMP manufacturing runs.
• Follow established SOPs and batch records in a cGLP laboratory environment.
• Support drafting and revision of SOPs, batch records, and technical documentation.
• Operate laboratory and analytical equipment after appropriate training.
• Accurately document experimental work following good documentation practices (GDP).
• Collaborate with cross-functional teams including Process Development, Analytical Sciences, and Manufacturing
• Maintain a safe, organized, and compliant laboratory workspace.
• Support inventory management team.

Education and Experience:

• BS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline.
• 0–2 years of laboratory experience (academic, co-op, internship, or industrial experience acceptable).

Knowledge, Skills and Abilities:

• Basic familiarity with analytical techniques such as pH, conductivity, HPLC, or LC-MS is preferred.
• Strong attention to detail and commitment to high-quality laboratory documentation.
• Willingness to learn regulated laboratory practices and manufacturing workflows.
• Ability to work collaboratively, follow instructions, and manage time effectively.