Associate Scientist II

Job Description

Job Summary:

• We are seeking a highly motivated and detail-oriented scientist to join our Humanized In Vitro Model Development team.
• The successful candidate will contribute to the development of human iPSC-derived neuronal models and assays to support drug discovery and translational research.
• This is an exciting opportunity to work at the forefront of human-relevant neuroscience in a collaborative and innovative environment.

Duties and Responsibilities:

• Culture, differentiate, and maintain human iPSC-derived neurons.
• Perform routine cell-based and molecular assays including immunocytochemistry, qPCR, ELISA, MEA, luciferase, western blot, and fluorescence microscopy.
• Conduct functional gene perturbations and pharmacological interventions.
• Support assay development and optimization for phenotypic screening and mechanistic studies.
• Analyze and interpret experimental data, maintain accurate records, and present findings in team meetings.
• Collaborate cross-functionally with scientists in different units.
• Contribute to protocol development, SOP documentation, and continuous improvement initiatives.

Education and Experience:

• Bachelor’s or Master’s degree in Neuroscience, Cell Biology, Stem Cell Biology, or a related field.
• LEVEL II – Minimum of 2 years of hands-on experience with human iPSC-derived neuronal cell models and assays.
• LEVEL III – Minimum of 5 years of hands-on experience with human iPSC-derived neuronal cell models and assays.
• Experience with CRISPR editing, RNA-seq, calcium imaging, high-content imaging, or complex co-culture systems is plus.

Knowledge, Skills and Abilities:

• Proficiency in cell-based assay techniques and fluorescence microscopy.
• Strong organizational and communication skills.
• Ability to work independently and collaboratively in a fast-paced research environment.
• Comfortable working with electronic lab notebooks.
• Knowledge of automated liquid handling systems and high-throughput screening platforms.
• Familiarity with cardiometabolic diseases is a plus.