Job Description
Job Summary:
- We are seeking a highly motivated candidate for an open position within the Cell Line Development (CLD) team creating recombinant CHO cell lines to support research and preclinical development programs within Client.
- The person in this role will work in a high-performing, fast-paced collaborative environment supporting end-to-end development of recombinant CHO cell lines and platform optimization for our future CHO expression platforms.
- Work will directly support the advancement of projects in Client’s biologics pipeline.
- Key responsibilities will include sterile cell culture techniques with suspension cultures, pool and clone generation, data assessment and communication, among other things.
Duties and Responsibilities:
- Assist in generation of engineered mammalian cell lines (transfection pools, clones) expressing candidate biotherapeutics
- Assist in several studies simultaneously to optimize cell line generation processes.
- Perform mammalian cell culture techniques: sterile technique, cell counting, passaging, cryopreservation, etc.
- Perform basic molecular biology techniques: DNA plasmid preparation, PCR, restriction enzyme digestion, etc.
- Self-motivated with excellent attention to detail and superb organizational skills.
- Proven ability to work in a highly collaborative environment and communicate transversally.
- Flexibility, adjusting to a fast-paced, goal-oriented environment and willingness to expand and broaden one’s skillset.
- Prepare reports, presentations, and data sets to effectively communicate results, progress and plans
Strong technical background. - Experience with data management, consolidation, and presentation.
- Contribute to lab organization, reagent tracking and other tasks as determined appropriate.
- Compliance with all applicable regulations, ensure that work performed is conducted in a safe and compliant manner, maintenance of proper records in accordance with SOPs and policies.
- Presentation of data at lab meetings.
Requirements:
- Bachelor’s Degree / Master’s Degree in Biology, Cellular Biology, Molecular Biology or equivalent (preferably in Cellular Biology research).
- Experience in suspension culture of CHO cell lines in a pharmaceutical or biotechnology setting.
- Knowledge of techniques such as cell culture and molecular manipulations.