Scientist IV

Job Description

Job Summary:

• We are looking for a highly motivated and innovative scientist to join the Target, Disease & Systems Biology (TDSB) department at Client as a Scientist.
• In this role, you will collaborate with the Pre-clinical Omics research team to investigate disease biology, uncover Client pathways and mechanisms, and identify strategies to address unmet medical needs across a range of therapeutic areas.
• This position offers the opportunity to apply cutting-edge molecular biology and spatial technologies to advance our therapeutic discovery efforts.
• The ideal candidate will bring strong technical expertise in bulk RNA-seq, single-cell/single-nucleus RNA-seq (sc/snRNA-seq), spatial transcriptomics, and spatial proteomics to support a broad Product of research initiatives.
• We are seeking someone who can lead and execute scientific research, analyze and present complex data, and communicate effectively with both expert and non-expert audiences.
• Strong organizational skills—including meticulous record keeping, planning and scheduling, and maintaining laboratory equipment—are essential.
• The successful candidate will be curious, Product, and creative in exploring new scientific directions and proposing innovative experimental approaches.
• At Client, we are an innovative global healthcare company driven by a singular purpose: to chase the miracles of science to improve people’s lives.
• We offer a dynamic environment where you can thrive professionally, build meaningful connections, and push the boundaries of scientific discovery.

Duties and Responsibilities:

1. Experimental Design & Execution:

• Design and perform experiments using bulk RNA-seq, single-cell/single-nucleus RNA-seq (sc/snRNA-seq), NGS and spatial assays (GeoMx, Visium, Xenium, Phenocycler-Fusion) on human and non-human biological samples.
• Optimize and troubleshoot protocols for molecular and spatial assays.

2. Data Analysis & Interpretation:

• Collaborate with bioinformatics teams to analyze high-dimensional omics data.
• Interpret results to guide therapeutic target identification and validation.

3. Technology Development & Innovation:

• Evaluate and implement emerging molecular biology and spatial technologies.
• Contribute to the development of Client workflows and platforms.

4. Cross-functional Collaboration:

• Work closely with scientists across biology, chemistry, and computational disciplines.
• Present findings in internal meetings and contribute to strategic research discussions.

5. Documentation & Reporting:

• Maintain detailed experimental records.
• Prepare technical reports and presentations.

Education and Experience:

• Master’s degree or Ph.D. in Molecular Biology, Cellular Biology, Genomics, or a related field.
• 3–5 years of relevant experience in academia or industry, with demonstrated expertise in transcriptomics and spatial biology.

Required qualifications:

• scRNA-seq and snRNA-seq.
• Bulk RNA-seq.
• Next-Gen Sequencing (NGS).

Preferred qualifications:

• Spatial transcriptomics platforms.
• Spatial proteomics technologies.
• Proficiency in tissue handling, imaging, and histological techniques.
• Familiarity with bioinformatics tools and pipelines for omics data analysis.
• Strong problem-solving skills and ability to work independently and collaboratively.
• Excellent communication and organizational skills.