Research Scientist

Job Description

Job Summary:

• We are seeking an experienced individual with oncology discovery and/or translational expertise to join the Translational Research team within the Client at in Cambridge, MA.
• The qualified candidate will work broadly with the research organization to support drug discovery programs, by conducting experimental work in a translational setting, including developing and implementing cutting-edge technology and Client cellular, molecular and biochemical assays in cancer research and deliver data for Oncology TRC programs.

Duties and Responsibilities:

• Design, optimize, and set up high-throughput screening cellular assays to characterize drug responses and combinations in various in vitro oncology models.
• Conduct molecular, biochemical and related assays including qPCR, ELISA, Western blot, immunostaining and basic microscopy.
• Develop biomarker, pharmacodynamic and target engagement assays.
• Execute, troubleshoot and interpret scientific experiments with some supervision.
• Effectively communicate and document experimental procedures, analyze results and data through study reports and internal meetings.
• Collaborate with other team members in areas of responsibility.

Education and Experience:

• Bachelor’s Degree with 3-5 years of academic and / or industry experience.
• Master’s Degree with 1-3 years of academic and / or industry experience in cellular biology, oncology and molecular biology in the pharma or biotech setting may be considered.
• Hands on experience in conducting cancer cell line and primary cell culture, expansion and functional assays.
• Experienced in the design and development of cell-based and molecular assays in a high-throughput manner.
• Experience performing analysis of protein and DNA/RNA samples using a variety of methodologies including but not limited to western blot, flow cytometry, qPCR, client /ELISA, RNAi, CRISPR.

Skills and Abilities:

• Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required.
• Excellent organizational skills and ability to maintain accurate, detailed record-keeping of laboratory data.
• Ability to summarize and interpret scientific data and communicate well with peers and supervisors.