Bench Scientist

Job Description

Job Summary:

• Summarize the primary purpose & key accountabilities of the position, including Product of responsibility in 5-7 concise sentences. (It may be helpful to complete this section after you have finished the other sections of the document.
• The client Inflammation & Immunology Research Unit (I&I RU) in Cambridge is looking for a Senior Scientist to join the in vivo group.
• The main responsibilities are to provide in vivo pharmacology expertise in models of neurodegenerative and neuroinflammatory diseases and to conduct and support mechanistic in vivo, in vitro and ex vivo studies.
• Key additional qualifications are expertise in rodent brain delivery techniques and immunohistology.
• Analyze data and present to project teams.
• A high level of autonomy is expected.

Duties and Responsibilities:

• In order of importance, list the primary responsibilities critical to the performance of the position.
• Please include actual tasks and/or essential responsibilities that highlight accountability and level of judgment required.
• Provide in vivo pharmacology expertise in in-vivo models of neurodegenerative diseases, ex-vivo analyses and autoimmunity.
• Develop, implement and conduct in-vivo efficacy studies and contribute to the mechanistic understanding of preclinical neuroinflammation-related studies.
• Execute preclinical mouse in vivo studies in the neuroinflammation/neurodegeneration space.
• This includes the establishment of new mouse models.
• Contribute to the mechanistic understanding of in vivo results by supporting ex vivo and in vitro analyses.
• Analyze, interpret, upload and present data in project team meetings.
• Serve as a resource to explore new avenues for preclinical research in neurodegeneration.

Education and Experience:

• Indicate the formal education, certification or license(s) required and/or preferred. Include the minimum number of years of relevant experience required for the position (where legally permissible).
• PhD, or Master’s Degree with 2+ years of experience or Bachelor’s degree with 4+ years of experience in the in vivo neuroinflammation and-or neurodegeneration scientific space.
• Working knowledge of biopharmaceutical research and drug discovery.

Technical Skills Requirements:

• Indicate the technical skills required and/or preferred, as applicable.
• Hands on experience with immunohistology, transcriptomic and proteomic methods and cell culture techniques.
• Hands-on in vivo expertise including mouse brain delivery techniques and rodent brain dissection
• Decision- and action-oriented, with a high level of autonomy.
• Excellent communication and analysis skills: ability to compute complex information to conclusion and recommendations.
• Hands on exp. molecular biology tech
• Small animal handling
• Independent worker
• Analyzing communication of data
• Hands-on experience in histology is a plus

Physical Requirements:

• Note the physical conditions in which work will be performed, if applicable to the position.
• Examples: Lifting, sitting, standing, walking, ability to travel, drive, unusual attendance requirements, weekend work or travel requirements, etc.
• Please include any hazardous materials or non-standard working environment the contractor will have exposure to which may require additional medical testing and/or apparatus fitting for OSHA compliance.
• Lifting.
• Sitting.
• Standing.
• Walking.
• Bending.

Interview Process:

• Teams (Camera-On).