Job Description
Job Summary:
- Seeking a highly motivated scientist with experience in liquid-handling automation to establish binding and functional assays to support hit-to-lead discovery of large molecule therapeutics.
- The candidate will play a critical role in the design and execution of biochemical and of cell-based functional assays and high-throughput screening to support the biologics portfolio.
- The candidate will be responsible for the design and execution of experiments using a variety of detection technologies that may include HTRF, ELISA/DELFIA, FACS, and cell-based functional assays focused on signaling, proliferation, or cytotoxicity.
- In addition, the candidate will analyze data, present results at internal meetings, and closely collaborate with project team members to develop strategies and identify lead molecules.
- We are looking for a creative, solution-oriented individual who products the opportunity to explore new methods.
Requirements:
- Assay Design/Validation and Data QC.
- Excellent cell culture experience, ability to maintain multiple lines in parallel.
- High Throughput Screening including use of automation including Beckman I series.
- Experience with assay technologies including ELISA, FACS, cell-based reporter assays, Alpha LISA and cytotoxicity.
- Familiar with analysis programs such as Gene Data Screener and GraphPad Prism, and LIMS programs such as Gene Data Biologics.