Proteomics Bench Scientist

Job Description

Job Summary:

• Candidate will be responsible for developing proteomics workflows using advanced high-resolution mass spectrometry techniques.
• Key duties include development and optimization of sample preparation methods from cell lines and other matrices for mass spectrometry analysis and data processing with various bioinformatics tools; collaborative work with colleagues; accurately documenting all activities in an electronic lab notebook (ELN).
• This role requires expertise in LC-MS based proteomics.
• Experience with cell culture and cell manipulation is a plus.

Duties and Responsibilities:

• Applying knowledge of proteomics workflows to develop and implement optimal strategies for the preparation and analysis of cellular samples.
• Working collaboratively with experts in the team to advance innovative proteomics strategies.
• Employing different bioinformatics tools for data analysis and fitting.
• Consistent record keeping using an electronic lab notebook (ELN).

Education and Experience:

• M.Sc. 5+ years, PhD 0+ years in a relevant scientific field with a documented experience in proteomics and mass-spectrometry.

Technical Requirements:

• Advanced knowledge and documented expertise with mass-spectrometry based proteomics approaches: label- or label-free quantification (TMT or DIA).
• Experience with high-resolution mass-spectrometry instruments, such as Orbitraps and times TOF.
• Experience with sample preparation based on enrichment (incl. affinity purification), and universal protein extraction.
• Bioinformatics skills relevant for mass-spec data search, statistical analysis and visualization.
• Experience with membrane protein analysis and/or cell surface proteomics.
• Knowledge of cell culture techniques and experience conducting cell-based assays.

Physical Requirements:

• Walking, taking the stairs, standing, sitting as appropriate for a laboratory-based position.

Interview:

• First round: Teams Meeting.
• Second round: onsite.