Synthesis Technician II

San Diego, California
July 10, 2025
$23 / hour
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Job Description

Job Summary:

  • The Technician II (Desalt Tubes) synthesizes, purifies, formulates and ensures the quality of custom OligonucleoProduct according to the customer’s order and internal specifications.
  • This generally includes, synthesis, cleavage, deprotection, purification, desalting, QC sampling, QC analysis and final packaging and formulation of the oligos and chemical reagents being made.

Duties and Responsibilities:

  • Synthesizes oligos on various synthesizer platforms.
  • Cleaves and deprotects oligos utilizing appropriate methods.
  • Quantifies and samples oligos for quality control tests.
  • Assesses QC data accurately and makes pass/fail decisions for oligos.
  • Performs the purification of oligos using various techniques.
  • Ensures that product meets final purity guarantees through the custom purification process.
  • Troubleshoots oligo failures and makes thoughtful sorting and purification decisions.
  • Keeps thorough records of specialized processes in the oligo process history.
  • Uses automated and manual lab equipment accurately; including limited maintenance, decontamination and troubleshooting activities.
  • Utilizes computers and custom software in a Windows-based environment to complete tasks and create final product.
  • Adheres to safety regulations, lab SOPs, and contamination controls.
  • Prepares, tests and monitors reagents for synthesis, purification, and quality control processes.
  • Prioritizes incoming orders to best meet guaranteed ship deadlines.
  • Follows documented custom instructions and aids, when applicable.
  • Analyzes data and information for quality, consistency, and accuracy.
  • Demonstrates behavior consistent with the Integrated DNA Technologies Core Values.
  • Performs other duties as assigned.

Education:

  • Associate’s degree in science related field plus 2 years of applicable lab experience required.
  • Bachelor’s degree in science related field preferred.

Experience:

  • Proficiency in a variety of PC software programs with strong working knowledge of Microsoft Office required.

Physical Requirements:

  • Exert 50-100 lbs. of force occasionally and/or 25-50 lbs. of force frequently Constant (67%-100% of work day)
  • Reaching: Using Fingers/Grasping/Feeling: Hearing: Repetitive Motion.
  • Frequently (34-66% of work day) Standing: Walking Lifting: Talking: Sitting: Bending: Pushing/Pulling: Climbing.

Visual Acuity:

  • Work requires close vision, distance vision, peripheral vision, depth perception and ability to adjust focus.
  • Ability to read pertinent printed material and distinguish colors.
  • Ability to accurately read measurements on equipment.
  • Ability to prepare and read written documentation; use of computer.

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