Job Description
Duties and Responsibilities:
- Culture, quality control (QC), and cell banking of diverse solid tumor cell lines.
- Engineer, culture and characterize CAR T cell function in vitro.
- Perform routine laboratory procedures including ddPCR, qPCR, Flow, Luminex/MSD for ELISA and various cell-based immunoassays and biochemical assays.
- Analyze, interpret, and translate results into actionable and tangible findings.
- Maintain accurate and detailed records of laboratory procedures, experimental designs, and results in compliance with organizational standards; familiarity with Benchling a plus.
- Design and execute fit-for-purpose or hypothesis-based experiments; analyze and interpret data to support development.
- Communicate effectively research plans and results, in both oral and written form.
- Coordinate tasks across multiple projects, work closely with cross-functional teams to support ongoing research projects, ensuring seamless integration of experimental findings.
- Contribute to a dynamic, exciting culture that embraces teamwork and innovation.
- Support the timeline-sensitive Pre-IND/IND research activity and work cross-functionally with different teams.
Basic Qualifications:
- Master’s Degree and 2+ years of related industry/academic Experience.
- Bachelor’s Degree and 4+ years of related industry/academic experience.
Preferred Qualifications:
- BS 6+ years or MS 3+ years or equivalent degree of relevant experience in Cell Biology and/or Immunology.
- Prior hands-on experience in the CAR-T field is preferred.
- Proficiency in experiment design, data analysis, interpretation, and presentation.
- Required high degree of accuracy and attention to details.
- Hands on experience with primary T cell isolation, culture and assays (e.g. cytotoxicity assays, cell proliferation assays, xCELLigence/eSight assays), multicolor flow cytometry, SCLC cell line culture and data analysis (FACSDiva, FlowJo, GraphPad, Prism, Excel).
- Experience with ex vivo CAR T manufacturing is preferred.
- Strong communication skills, both written and verbal.
- The ideal candidate should be flexible to meet team’s priorities and willing to support team members with their projects.