Job Description
Job Summary:
- Client is seeking a talented and highly motivated individual to join our Research Oncology team.
- This role offers the opportunity to provide scientific support for key laboratory activities, including cell culture and cell line characterization.
- The candidate will collaborate on various projects, working with colleagues cross-functionally in a fast-paced, resource-rich environment, and will have opportunities for professional growth through the acquisition of new skills and experiences.
Duties and Responsibilities:
- Responsible for the expansion, maintenance, cryopreservation, and thawing of multiple cell lines.
- This includes ensuring proper handling of cell lines and preparation of media with complex supplements.
- Collaborate with team members to assess cell culture needs and provide necessary support for ongoing research activities.
- Engage with various functional areas to evaluate cell culture and cell banking needs and deliver materials according to defined timelines.
- Understand quality control procedures to validate cell lines as needed to ensure experimental integrity.
- Maintain accurate, detailed laboratory notebooks and relevant documentation for all laboratory activities.
- Opportunities to contribute to the development and implementation of genetically modified cell lines and in vitro cell-based assays to support various Client Oncology projects.
Basic Qualifications:
- B.S. degree in Molecular Biology, Cell Biology, Cancer Biology, or a related life science field, with a minimum of 3 years of hands-on experience working with cancer cell lines, primary cells, and genetically engineered cell lines.
- Expertise in aseptic technique and mammalian cell culture, including handling multiple cell lines. simultaneously and preparing media with complex supplements.
- Excellent organizational skills, attention to detail, and proficiency in record keeping.
- Familiarity with cell culture quality control practices such as mycoplasma testing and cell line. authentication.
Preferred Qualifications:
- B.S. degree in Molecular Biology, Cell Biology, Cancer Biology, or a related life science field, with a minimum of 6 years of strong hands-on experience in mammalian cell culture in the biopharmaceutical or biotechnology industry.
- Proficiency in using electronic lab notebooks for experiment documentation, inventory management, and workflow execution.
- Experience optimizing and troubleshooting mammalian cell culture systems.
- Exceptional organizational skills with meticulous attention to detail and data integrity.
- Strong written and verbal communication abilities.
- Experience in writing and maintaining standard operating procedures (SOPs).
- Experience with online genetic databases and the ability to advise on integrating relevant phenotypic and genetic information into our cell bank management systems.
- Experience with biology techniques such as viral and non-viral transduction or transfection methods (e.g., lentivirus, retrovirus, lipid-based systems).
- Experience and familiarity with laboratory instruments such as plate readers, cell counters, and automated western blot systems.
- Ability to run basic cell assays and develop cell line banking protocols.
- Adaptability in a fast-paced environment with shifting priorities and timelines.