Associate Scientist – Biology II

Job Description

Job Summary:

• We are seeking an Associate Scientist to join Client’s In Vivo Pharmacology team in Foster City and more specifically the group responsible to conduct ex vivo analyses related to in vivo studies in mice.
• The candidate will join an established group, playing a key role in providing a mechanistic understanding for in vivo pre-clinical studies in support of multiple programs utilizing engineered human chimeric antigen receptor T cells (CAR T cells).

Duties and Responsibilities:

• Characterization of immune parameters such as cell expansion and phenotype, from ex vivo blood samples from pre-clinical mouse studies with engineered human CAR T cells.
• Process and analyze ex vivo blood samples through flow cytometry, molecular biology and other analytical techniques.
• Check antigen expression by flow cytometry of tumor cell lines for use in in vivo studies.
• Work collaboratively in a cross-functional team environment.
• Present and participate in project team meetings and cross-departmental team meetings.
• Share core values such as passion, teamwork, integrity and trust.

Education and Experience:

• Master’s Degree and 2+ years of scientific experience.
• Bachelor’s Degree and 4+ years of scientific experience.
• AA Degree and 5+ years of scientific experience.
• High School Degree and 6+ years of scientific experience.
• MS or BS in Biology or related discipline.
• 3+ years of experience with multi-color flow cytometry and complex fluorochrome-conjugated antibody panels.
• Immunology background, with experience in phenotypic analysis of multiple human immune cell populations and markers of activation/exhaustion.
• Experience in data analysis software including FlowJo, GraphPad Prism and FACSDiva.
• Experience in additional molecular biology techniques such as ddPCR.

Knowledge, Skills and Abilities:

• Demonstrated ability to independently conduct analyses while working efficiently as part of a team.
• Ability to multi-task, perform work with a high degree of integrity and attention to detail, and be part of an exciting fast-paced scientific environment.
• Strong organizational and time-management skills, thorough record keeping skills (documentation and electronic lab notebook, Benchling), strong ability to troubleshoot independently and to provide high-quality results through critical analysis and interpretation, excellent interpersonal, verbal and written communication skills.